If you build a tolerance on 1 substance that affects serotonin, will that also build your tolerance to other substances that does the same thing?

I've been using eutylone atleast once a week since December because it's cheaper than mdma and now It's losing its euphoria and just fucking me up. I've read about people losing the magic of mdma and I'm scared when I do it again I've lost the magic too. Also does waiting awhile bring back the euphoria?

Edit: Waited a little over a month and it came back with the same stuff, still not as strong as the first time but it was good. Abusing it is just wasting money for nothing.