Thinking about starting a 3rd playthrough and wondering about some fun ways to make things more interesting/challenging by handicapping myself..?

I want it to be challenging but obviously not impossible. What are some ways you guys do that?

Some ways I was thinking...

Only using weapons found in the wild (so no purchased weapons and no weapons from boxes)

No parkour (basically playing like a normal dude, although this sounds kinda unfun)

Only doing missions at night.

No crafting health kits.

____________???