Third Rune Strategy
All my (very few) wins so far have been brutes, and every third rune was Silver. I've been using the "Read ?Tele then go down stairs" strategy that the wiki recommended. Playing a Poltergeist Enchanter of Dithmenos this time, I have Discord at 51% Power and 4% Fail, as well as Enfeeble and Dispersal at 1% Fail.
Would it be best if I greet the ambush party with a big Discord, then try to go up if there's no Wardens/use Dispersal to keep the angry guards away from me if there are wardens; try to get the Slimy or Abyssal runes instead; or just use my normal V:5 strategy?
The main strategy I've heard for Slime involves multiple ?Torment, of which I only have 1, but I could possibly do ?Torment into Discord if that works on slimes.
Edit: Thanks for the advice! Torment spawned only infinite-willpower slimes, but a couple javelins were enough to get a Discord ready. Two Discords and an ?immo later and the Slimy Rune was mine. Ended up getting my seventh Orb from this run!