80s Resto Mod Advice

I'm in the process of planning out a resto-mod of an 80s frame that I own. The frame is a FUSO from the late 80s and uses a BSA BB (~68/70mm).

I'm planning to go with a Shimano R7000 105 groupset (with the GS RDR). I will probably get a Wolf Tooth road-link to extend the range of the RDR so that I can use a 40 or 42 cassette.

My Question: Can anyone think of any reason that this groupset won't work with the frame? E.g., will the chain line with a new external BB (e.g., the Shimano BBR60) be an issue? FWIW, I am planning to buy new wheels, get the frame cold set to the appropriate width, buy a quill stem adapter for new bars, etc. so my questions revolve around the frame groupset interaction.

Also, I'm going to cross-post this on Vintag_bicycles.

Thanks.