How does smoking work on hrt

Here’s the thing, I know smoking is bad for me, I’ve always known that, but if I’m being truthful, I’ve been vaping more than smoking cigarettes, I know it’s equally bad, but I’m ready to start hrt, possibly this Friday, and I’m wondering how it works with my habit, like could I take my injections before I hit the vape or?? I’m just confused about it, so some help would be great hehe~ I also smoke weed too, but I’m pretty sure that’s okay to do on hrt