NSI-189 while on SSRI: Is it safe? Has anyone tried it

Hi everyone,

I recently stopped taking Brintellix (vortioxetine) about two days ago and decided to try NSI-189. So far, I haven’t experienced any negative effects—if there were a problematic interaction, I imagine I’d have felt worse. Since NSI-189 isn’t serotonergic, I was wondering if anyone else has made a similar switch or combined these two in any way.

Has anyone had experience with transitioning from Brintellix to NSI-189 or using them concurrently? I’d appreciate any insights or advice regarding potential interactions or side effects.

Thanks in advance!