Ten days in Berlin, which neighborhood should I stay in?

I'm visiting Berlin for 10 days in May with my partner. I've been looking at airbnb and am trying to decide between Kreuzberg and PrenzlauerBerg. I'm posting here so obviously we are not fancy people, just looking to enjoy the city and relax for a bit. Any insight into the neighborhoods (which I understand are more to the scale of nyc boroughs) is much appreciated!

Side note- are full apartment air bnbs banned there and am I wasting my time/getting scammed? lol

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EDIT TO ADD: I am also looking at Wedding! Thoughts?