Was anyone ever able to go off all medication?

I was able to stop taking doxycycline, and I’ve been hoping to stop using metrogel as well. I recently tried stepping off by decreasing use from twice per to day to once, and was hoping to start using every other day, etc, but within a couple days I started getting some painful pustules on my nose, and flushing was happening at like the drop of a hat. Were any of you successful at being able to stop using medication?

Edit- thanks to all who responded. To clarify, I am not on doxycycline anymore, I use metrogel, which is topical, and is what I attempted to taper off of. I do appreciate hearing about folks experiences.