Picking my DMT

My Ask: Tysabri or Kesimpta. Any experiences you could share with either (or bonus if you've been treated with both), would be most appreciated.

Hello Internet Strangers! I am recently diagnosed and working on choosing my DMT. Tysabri has been Dr.'s recommendation, but also was told any of these other three (Ocrevus, Kesimpta, Zeposia) would be good but we want to treat aggressively. I've narrowed it down to Tysabri or Kesimpta. I was sort of hoping my JC Virus test would help make the decision, and well it just came back and I am negative;

I have done a ton of research and have pros and cons about both, but am at a loss. I am normally pretty decisive, this one just worries me because there seems like so much riding on it. Thank you all!