You can delete comments and block people on AO3
I keep seeing people making posts about mean comments they’ve gotten on their fic. I’ve been lucky enough to never get more than a couple of these, but every single time I have just deleted the comment and blocked that person on AO3 (this prevents them from ever commenting on any of your fic again). I never bother replying. I don’t see that there’s ever a reason to give someone so rude the time of day.